Bitte benutzen Sie diese Referenz, um auf diese Ressource zu verweisen:
doi:10.22028/D291-46689 | Titel: | Clinical Outcomes of Minced Cartilage Treatment (AutoCart™) for Medial Osteochondral Lesions of the Talus: A Prospective One-Year Follow-Up Study |
| VerfasserIn: | Roth, Klaus E. Salzmann, Gian M. Winter, Philipp Schmidtmann, Irene Maier, Gerrit Cochrane, Isabelle Ossendorff, Robert Klos, Kajetan Drees, Philipp |
| Sprache: | Englisch |
| Titel: | Journal of Clinical Medicine |
| Bandnummer: | 14 |
| Heft: | 24 |
| Verlag/Plattform: | MDPI |
| Erscheinungsjahr: | 2025 |
| Freie Schlagwörter: | minced cartilage implantation cartilage regeneration talus ankle |
| DDC-Sachgruppe: | 610 Medizin, Gesundheit |
| Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
| Abstract: | Background/Objectives: This prospective study aims to assess the clinical outcomes of the AutoCart™ technique for the treatment of medial osteochondral lesions of the talus (OLT). Methods: 29 consecutive patients treated for medial OLT were included. Demographic char acteristics and preoperative imaging (MRI and CT) were reviewed, and patient-reported outcome measures (PROMs)—including a Visual Analog Pain Scale (VAS), Foot Function In dex (FFI), Foot and Ankle Ability Measure (FAAM), and the Veterans RAND 12-Item Health Survey (VR-12)—were assessed preoperatively and at 6 and 12 months post-treatment. Results: In the cohort, 14 (48%) were female, 13 (45%) were male, and 2 (7%) did not disclose their gender. Median age was 35.5 years (interquartile range: 23.0–49.5). Mean defect size was 121.95 ± 84.46 mm2 . Three patients were treated entirely arthroscopically, while 26 patients underwent medial malleolar osteotomy with cancellous bone grafting from the calcaneus for cartilage fragment placement. At one-year follow-up, there were significant improvements in pain and functional outcomes. The VAS score showed a mean reduction of 1.3 points (95% CI: −2.6 to −0.1; p = 0.036). Strong improvement was observed in the FFI, with a mean reduction of 13.3 points (95% CI: −21.0 to −5.6; p = 0.001). The FAAM Sports subscale showed a significant increase of 18.6 points (95% CI: 7.0 to 30.1; p = 0.002). Conclusions: Patients demonstrate clinical improvement after minced cartilage implantation with the AutoCart™ technique. These findings suggest that the minced cartilage procedure is a viable treatment option for medial OLTs, though further studies are needed to assess long-term efficacy. |
| DOI der Erstveröffentlichung: | 10.3390/jcm14248710 |
| URL der Erstveröffentlichung: | https://doi.org/10.3390/jcm14248710 |
| Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-466890 hdl:20.500.11880/40929 http://dx.doi.org/10.22028/D291-46689 |
| ISSN: | 2077-0383 |
| Datum des Eintrags: | 5-Jan-2026 |
| Bezeichnung des in Beziehung stehenden Objekts: | Supplementary Materials |
| In Beziehung stehendes Objekt: | https://www.mdpi.com/article/10.3390/jcm14248710/s1 |
| Fakultät: | M - Medizinische Fakultät |
| Fachrichtung: | M - Orthopädie |
| Professur: | M - Prof. Dr. Stefan Landgraeber |
| Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
| Datei | Beschreibung | Größe | Format | |
|---|---|---|---|---|
| jcm-14-08710.pdf | 3,01 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons

