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doi:10.22028/D291-37095 | Title: | Exhaled Aldehydes as Biomarkers for Lung Diseases : A Narrative Review |
| Author(s): | Floss, Maximilian Alexander Fink, Tobias Maurer, Felix Volk, Thomas Kreuer, Sascha Müller-Wirtz, Lukas Martin |
| Language: | English |
| Title: | Molecules |
| Volume: | 27 |
| Issue: | 16 |
| Publisher/Platform: | MDPI |
| Year of Publication: | 2022 |
| Free key words: | aldehydes lipid peroxidation oxidative stress volatile organic compounds biomarker |
| DDC notations: | 610 Medicine and health |
| Publikation type: | Journal Article |
| Abstract: | Breath analysis provides great potential as a fast and non-invasive diagnostic tool for several diseases. Straight-chain aliphatic aldehydes were repeatedly detected in the breath of patients suffering from lung diseases using a variety of methods, such as mass spectrometry, ion mobility spectrometry, or electro-chemical sensors. Several studies found increased concentrations of exhaled aldehydes in patients suffering from lung cancer, inflammatory and infectious lung diseases, and mechanical lung injury. This article reviews the origin of exhaled straight-chain aliphatic aldehydes, available detection methods, and studies that found increased aldehyde exhalation in lung diseases. |
| DOI of the first publication: | 10.3390/molecules27165258 |
| Link to this record: | urn:nbn:de:bsz:291--ds-370957 hdl:20.500.11880/33687 http://dx.doi.org/10.22028/D291-37095 |
| ISSN: | 1420-3049 |
| Date of registration: | 29-Aug-2022 |
| Faculty: | M - Medizinische Fakultät |
| Department: | M - Anästhesiologie |
| Professorship: | M - Prof. Dr. Thomas Volk |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
| File | Description | Size | Format | |
|---|---|---|---|---|
| molecules-27-05258-v2.pdf | 3,25 MB | Adobe PDF | View/Open |
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