Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
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article | 2024 | Quantitative analysis of drugs of abuse and cognitive enhancers in influent wastewater by means of two chromatographic methods | Frankenfeld, Fabian; Wagmann, Lea; Jacobs, Cathy M.; Meyer, Markus R. | |
article | 2024 | Studying drug excretion into exhaled breath aerosol - A workflow based on an impaction sampling device and LC-HRMS/MS analysis | Maalouli Schaar, Juel; Kunz, Michael; Wagmann, Lea; Beck, Olof; Mahfoud, Felix; Meyer, Markus R. | |
article | 2024 | In Vivo and In Vitro Metabolic Fate and Urinary Detectability of Five Deschloroketamine Derivatives Studied by Means of Hyphenated Mass Spectrometry | Frankenfeld, Fabian; Wagmann, Lea; Abelian, Anush; Wallach, Jason; Adejare, Adeboye; Brandt, Simon D.; Meyer, Markus R. | |
article | 2024 | Towards clinical adherence monitoring of oral endocrine breast cancer therapies by LC-HRMS-method development, validation, comparison of four sample matrices, and proof of concept | Jacobs, Cathy M.; Radosa, Julia C.; Wagmann, Lea; Zimmermann, Julia S. M.; Kaya, Askin C.; Aygün, Aylin; Edel, Tatjana; Stotz, Lisa; Ismaeil, Mohamed; Solomayer, Erich-Franz; Meyer, Markus R. | |
article | 2024 | Impact of four different extraction methods and three different reconstitution solvents on the untargeted metabolomics analysis of human and rat urine samples | Hemmer, Selina; Manier, Sascha K.; Wagmann, Lea; Meyer, Markus R. | |
article | 2024 | Metabolism and cytotoxicity studies of the two hallucinogens 1cP-LSD and 4-AcO-DET in human liver and zebrafish larvae models using LC-HRMS/MS and a high-content screening assay | Gampfer, Tanja M.; Schütz, Victoria; Schippers, Philip; Rasheed, Sari; Baumann, Jonas; Wagmann, Lea; Pulver, Benedikt; Westphal, Folker; Flockerzi, Veit; Müller, Rolf; Meyer, Markus R. | |
article | 2024 | Prevalence of Drugs of Abuse and Cognitive Enhancer Consumption Monitored in Grab Samples and Composite Wastewater via Orbitrap Mass Spectrometry Analysis | Frankenfeld, Fabian; Wagmann, Lea; Jacobs, Cathy M.; Meyer, Markus R. | |
article | 2024 | Comparison of reversed-phase, hydrophilic interaction, and porous graphitic carbon chromatography columns for an untargeted toxicometabolomics study in pooled human liver microsomes, rat urine, and rat plasma | Hemmer, Selina; Manier, Sascha K.; Wagmann, Lea; Meyer, Markus R. | |
article | 2024 | Rapid analysis of amatoxins in human urine by means of affinity column chromatography and liquid chromatography-high-resolution tandem mass spectrometry | Vollmer, Aline C.; Fecher-Trost, Claudia; Bever, Candace S.; Tam, Christina C.; Wagmann, Lea; Meyer, Markus R. | |
article | 2023 | Efficacy of Antihypertensive Drugs of Different Classes After Renal Denervation in Spontaneously Hypertensive Rats | Hohl, Mathias; Lauder, Lucas; Sevimli, Özlem; Tokcan, Mert; Wagmann, Lea; Götzinger, Felix; Schneider, Clara; Hübner, Ulrich; Lehnert, Ulrike; Meyer, Markus R.; Böhm, Michael; Mahfoud, Felix | |
article | 2023 | Evaluation of extraction methods for untargeted metabolomic studies for future applications in zebrafish larvae infection models | Schippers, Philip; Rasheed, Sari; Park, Yu Mi; Risch, Timo; Wagmann, Lea; Hemmer, Selina; Manier, Sascha K.; Müller, Rolf; Herrmann, Jennifer; Meyer, Markus R. | |
article | 2022 | Reviewing toxicokinetics with a focus on metabolism of new psychoactive substances in the zebrafish (larvae) model | Wagmann, Lea; Meyer, Markus R. | |
article | 2022 | In vitro metabolic fate of the synthetic cannabinoid receptor agonists (quinolin-8-yl 4-methyl-3-(morpholine-4-sulfonyl)benzoate [QMMSB]) and (quinolin-8-yl 4-methyl-3-((propan-2-yl)sulfamoyl)benzoate [QMiPSB]) including isozyme mapping and carboxylesterases activity testing | Richter, Matthias J.; Wagmann, Lea; Kavanagh, Pierce V.; Brandt, Simon D.; Meyer, Markus R. | |
article | 2022 | Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterases | Wagmann, Lea; Stiller, Rebecca G.; Fischmann, Svenja; Westphal, Folker; Meyer, Markus R. | |
article | 2022 | In Vitro and In Vivo Toxicometabolomics of the Synthetic Cathinone PCYP Studied by Means of LC-HRMS/MS | Hemmer, Selina; Wagmann, Lea; Pulver, Benedikt; Westphal, Folker; Meyer, Markus R. | |
article | 2022 | Closing the gap : development of an analytical methodology using volumetric absorptive microsampling of finger prick blood followed by LC-HRMS/MS for adherence monitoring of antihypertensive drugs | Jacobs, Cathy M.; Kunz, Michael; Mahfoud, Felix; Wagmann, Lea; Meyer, Markus R. | |
article | 2022 | Analytical toxicology of yew constituents in human blood and urine by liquid chromatography-high-resolution tandem mass spectrometry | Jacobs, Cathy M.; Wagmann, Lea; Meyer, Markus R. | |
article | 2021 | Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose | Hemmer, Selina; Wagmann, Lea; Meyer, Markus R. | |
article | 2021 | Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systems | Gampfer, Tanja M.; Wagmann, Lea; Belkacemi, Anouar; Flockerzi, Veit; Meyer, Markus R. | |
article | 2021 | Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis | Wagmann, Lea; Vollmer, Aline C.; Lauder, Lucas; Mahfoud, Felix; Meyer, Markus R. | |
article | 2021 | Development, validation, and application of a quantitative volumetric absorptive microsampling-based method in finger prick blood by means of LC-HRMS/MS applicable for adherence monitoring of antipsychotics | Jacobs, Cathy M.; Wagmann, Lea; Meyer, Markus R. | |
article | 2021 | Recent trends in drugs of abuse metabolism studies for mass spectrometry-based analytical screening procedures | Wagmann, Lea; Gampfer, Tanja M.; Meyer, Markus R. | |
article | 2021 | Abuse of nutmeg seeds: Detectable by means of liquid chromatography-mass spectrometry techniques? | Manier, Sascha K.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R. | |
article | 2021 | In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists QMPSB and QMPCB (SGT-11) Including Isozyme Mapping and Esterase Activity | Richter, Matthias J.; Wagmann, Lea; Gampfer, Tanja M.; Brandt, Simon D.; Meyer, Markus R. | |
article | 2021 | Further development of a liquid chromatography-high-resolution mass spectrometry/mass spectrometry-based strategy for analyzing eight biomarkers in human urine indicating toxic mushroom or Ricinus communis ingestions | Bambauer, Thomas P.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R. | |
article | 2021 | Toxic plants-Detection of colchicine in a fast systematic clinical toxicology screening using liquid chromatography-mass spectrometry | Vollmer, Aline C.; Wagmann, Lea; Meyer, Markus R. | |
article | 2020 | How to Study the Metabolism of New Psychoactive Substances for the Purpose of Toxicological Screenings — A Follow-Up Study Comparing Pooled Human Liver S9, HepaRG Cells, and Zebrafish Larvae | Wagmann, Lea; Frankenfeld, Fabian; Park, Yu Mi; Herrmann, Jennifer; Fischmann, Svenja; Westphal, Folker; Müller, Rolf; Flockerzi, Veit; Meyer, Markus R. | |
Other | 2020 | Addendum: Hemmer, S., et al. Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data. Metabolites 2020, 10, 378 | Hemmer, Selina; Manier, Sascha K.; Fischmann, Svenja; Westphal, Folker; Wagmann, Lea; Meyer, Markus R. | |
article | 2020 | Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry | Bambauer, Thomas P.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R. | |
article | 2020 | Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data | Hemmer, Selina; Manier, Sascha K.; Fischmann, Svenja; Westphal, Folker; Wagmann, Lea; Meyer, Markus R. | |
article | 2020 | Liquid Chromatography-High-Resolution Mass Spectrometry-Based In Vitro Toxicometabolomics of the Synthetic Cathinones 4-MPD and 4-MEAP in Pooled Human Liver Microsomes | Manier, Sascha K.; Schwermer, Florian; Wagmann, Lea; Eckstein, Niels; Meyer, Markus R. | |
article | 2020 | Toxicokinetics and toxicodynamics of the fentanyl homologs cyclopropanoyl-1-benzyl-4´-fluoro-4-anilinopiperidine and furanoyl-1-benzyl-4-anilinopiperidine | Gampfer, Tanja M.; Wagmann, Lea; Park, Yu Mi; Cannaert, Annelies; Herrmann, Jennifer; Fischmann, Svenja; Westphal, Folker; Stove, Christophe P.; Meyer, Markus R.; Müller, Rolf | |
article | 2020 | Toxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts | Manier, Sascha K.; Wagmann, Lea; Flockerzi, Veit; Meyer, Markus R. | |
article | 2019 | In vitro metabolic fate of nine LSD-based new psychoactive substances and their analytical detectability in different urinary screening procedures | Wagmann, Lea; Richter, Lilian; Kehl, Tobias; Wack, Franziska; Pettersson Bergstrand, Madeleine; Brandt, Simon D.; Stratford, Simon; Maurer, Hans H.; Meyer, Markus R. | |
article | 2019 | Toxicokinetic studies of the four new psychoactive substances 4-chloroethcathinone, N-ethylnorpentylone, N-ethylhexedrone, and 4-fluoro-alpha-pyrrolidinohexiophenone | Wagmann, Lea; Manier, Sascha K.; Eckstein, Niels; Maurer, Hans H.; Meyer, Markus R. | |
article | 2019 | Method development for quantitative determination of seven statins including four active metabolites by means of high-resolution tandem mass spectrometry applicable for adherence testing and therapeutic drug monitoring | Wagmann, Lea; Hemmer, Selina; Caspar, Achim T.; Meyer, Markus | |
article | 2019 | Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screenings | Wagmann, Lea; Hempel, Nora; Richter, Lilian H. J.; Brandt, Simon D.; Stratford, Alexander; Meyer, Markus R. | |
article | 2019 | Toxicokinetics and analytical toxicology of the abused opioid U-48800 - in vitro metabolism, metabolic stability, isozyme mapping, and plasma protein binding | Gampfer, Tanja M.; Richter, Lilian H. J.; Schäper, Jan; Wagmann, Lea; Meyer, Markus R. | |
article | 2018 | Inhibition and stimulation of the human breast cancer resistance protein as in vitro predictor of drug–drug interactions of drugs of abuse | Wagmann, Lea; Maurer, Hans H.; Meyer, Markus R. | |
article | 2018 | Interactions of phenethylamine‐derived psychoactive substances of the 2C‐series with human monoamine oxidases | Wagmann, Lea; Brandt, Simon D.; Stratford, Alexander; Maurer, Hans H.; Meyer, Markus R. | |
article | 2017 | An easy and fast adenosine 5'-diphosphate quantification procedure based on hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry for determination of the in vitro adenosine 5'-triphosphatase activity of the human breast cancer resistance protein ABCG2 | Wagmann, Lea; Maurer, Hans H.; Meyer, Markus R. | |
article | 2017 | In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risks | Wagmann, Lea; Brandt, Simon D.; Kavanagh, Pierce V.; Maurer, Hans H.; Meyer, Markus R. | |
article | 2016 | What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse? | Wagmann, Lea; Meyer, Markus R.; Maurer, Hans H. | |