List of publications

DokumenttypErscheinungsjahrTitelAutorenHerausgeber
article2024Quantitative analysis of drugs of abuse and cognitive enhancers in influent wastewater by means of two chromatographic methodsFrankenfeld, Fabian; Wagmann, Lea; Jacobs, Cathy M.; Meyer, Markus R.
article2024Studying drug excretion into exhaled breath aerosol - A workflow based on an impaction sampling device and LC-HRMS/MS analysisMaalouli Schaar, Juel; Kunz, Michael; Wagmann, Lea; Beck, Olof; Mahfoud, Felix; Meyer, Markus R.
article2024In Vivo and In Vitro Metabolic Fate and Urinary Detectability of Five Deschloroketamine Derivatives Studied by Means of Hyphenated Mass SpectrometryFrankenfeld, Fabian; Wagmann, Lea; Abelian, Anush; Wallach, Jason; Adejare, Adeboye; Brandt, Simon D.; Meyer, Markus R.
article2024Towards clinical adherence monitoring of oral endocrine breast cancer therapies by LC-HRMS-method development, validation, comparison of four sample matrices, and proof of conceptJacobs, Cathy M.; Radosa, Julia C.; Wagmann, Lea; Zimmermann, Julia S. M.; Kaya, Askin C.; Aygün, Aylin; Edel, Tatjana; Stotz, Lisa; Ismaeil, Mohamed; Solomayer, Erich-Franz; Meyer, Markus R.
article2024Impact of four different extraction methods and three different reconstitution solvents on the untargeted metabolomics analysis of human and rat urine samplesHemmer, Selina; Manier, Sascha K.; Wagmann, Lea; Meyer, Markus R.
article2024Metabolism and cytotoxicity studies of the two hallucinogens 1cP-LSD and 4-AcO-DET in human liver and zebrafish larvae models using LC-HRMS/MS and a high-content screening assayGampfer, Tanja M.; Schütz, Victoria; Schippers, Philip; Rasheed, Sari; Baumann, Jonas; Wagmann, Lea; Pulver, Benedikt; Westphal, Folker; Flockerzi, Veit; Müller, Rolf; Meyer, Markus R.
article2024Prevalence of Drugs of Abuse and Cognitive Enhancer Consumption Monitored in Grab Samples and Composite Wastewater via Orbitrap Mass Spectrometry AnalysisFrankenfeld, Fabian; Wagmann, Lea; Jacobs, Cathy M.; Meyer, Markus R.
article2024Comparison of reversed-phase, hydrophilic interaction, and porous graphitic carbon chromatography columns for an untargeted toxicometabolomics study in pooled human liver microsomes, rat urine, and rat plasmaHemmer, Selina; Manier, Sascha K.; Wagmann, Lea; Meyer, Markus R.
article2024Rapid analysis of amatoxins in human urine by means of affinity column chromatography and liquid chromatography-high-resolution tandem mass spectrometryVollmer, Aline C.; Fecher-Trost, Claudia; Bever, Candace S.; Tam, Christina C.; Wagmann, Lea; Meyer, Markus R.
article2023Efficacy of Antihypertensive Drugs of Different Classes After Renal Denervation in Spontaneously Hypertensive RatsHohl, Mathias; Lauder, Lucas; Sevimli, Özlem; Tokcan, Mert; Wagmann, Lea; Götzinger, Felix; Schneider, Clara; Hübner, Ulrich; Lehnert, Ulrike; Meyer, Markus R.; Böhm, Michael; Mahfoud, Felix
article2023Evaluation of extraction methods for untargeted metabolomic studies for future applications in zebrafish larvae infection modelsSchippers, Philip; Rasheed, Sari; Park, Yu Mi; Risch, Timo; Wagmann, Lea; Hemmer, Selina; Manier, Sascha K.; Müller, Rolf; Herrmann, Jennifer; Meyer, Markus R.
article2022Reviewing toxicokinetics with a focus on metabolism of new psychoactive substances in the zebrafish (larvae) modelWagmann, Lea; Meyer, Markus R.
article2022In vitro metabolic fate of the synthetic cannabinoid receptor agonists (quinolin-8-yl 4-methyl-3-(morpholine-4-sulfonyl)benzoate [QMMSB]) and (quinolin-8-yl 4-methyl-3-((propan-2-yl)sulfamoyl)benzoate [QMiPSB]) including isozyme mapping and carboxylesterases activity testingRichter, Matthias J.; Wagmann, Lea; Kavanagh, Pierce V.; Brandt, Simon D.; Meyer, Markus R.
article2022Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterasesWagmann, Lea; Stiller, Rebecca G.; Fischmann, Svenja; Westphal, Folker; Meyer, Markus R.
article2022In Vitro and In Vivo Toxicometabolomics of the Synthetic Cathinone PCYP Studied by Means of LC-HRMS/MSHemmer, Selina; Wagmann, Lea; Pulver, Benedikt; Westphal, Folker; Meyer, Markus R.
article2022Closing the gap : development of an analytical methodology using volumetric absorptive microsampling of finger prick blood followed by LC-HRMS/MS for adherence monitoring of antihypertensive drugsJacobs, Cathy M.; Kunz, Michael; Mahfoud, Felix; Wagmann, Lea; Meyer, Markus R.
article2022Analytical toxicology of yew constituents in human blood and urine by liquid chromatography-high-resolution tandem mass spectrometryJacobs, Cathy M.; Wagmann, Lea; Meyer, Markus R.
article2021Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine doseHemmer, Selina; Wagmann, Lea; Meyer, Markus R.
article2021Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systemsGampfer, Tanja M.; Wagmann, Lea; Belkacemi, Anouar; Flockerzi, Veit; Meyer, Markus R.
article2021Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry AnalysisWagmann, Lea; Vollmer, Aline C.; Lauder, Lucas; Mahfoud, Felix; Meyer, Markus R.
article2021Development, validation, and application of a quantitative volumetric absorptive microsampling-based method in finger prick blood by means of LC-HRMS/MS applicable for adherence monitoring of antipsychoticsJacobs, Cathy M.; Wagmann, Lea; Meyer, Markus R.
article2021Recent trends in drugs of abuse metabolism studies for mass spectrometry-based analytical screening proceduresWagmann, Lea; Gampfer, Tanja M.; Meyer, Markus R.
article2021Abuse of nutmeg seeds: Detectable by means of liquid chromatography-mass spectrometry techniques?Manier, Sascha K.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R.
article2021In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists QMPSB and QMPCB (SGT-11) Including Isozyme Mapping and Esterase ActivityRichter, Matthias J.; Wagmann, Lea; Gampfer, Tanja M.; Brandt, Simon D.; Meyer, Markus R.
article2021Further development of a liquid chromatography-high-resolution mass spectrometry/mass spectrometry-based strategy for analyzing eight biomarkers in human urine indicating toxic mushroom or Ricinus communis ingestionsBambauer, Thomas P.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R.
article2021Toxic plants-Detection of colchicine in a fast systematic clinical toxicology screening using liquid chromatography-mass spectrometryVollmer, Aline C.; Wagmann, Lea; Meyer, Markus R.
article2020How to Study the Metabolism of New Psychoactive Substances for the Purpose of Toxicological Screenings — A Follow-Up Study Comparing Pooled Human Liver S9, HepaRG Cells, and Zebrafish LarvaeWagmann, Lea; Frankenfeld, Fabian; Park, Yu Mi; Herrmann, Jennifer; Fischmann, Svenja; Westphal, Folker; Müller, Rolf; Flockerzi, Veit; Meyer, Markus R.
Other2020Addendum: Hemmer, S., et al. Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data. Metabolites 2020, 10, 378Hemmer, Selina; Manier, Sascha K.; Fischmann, Svenja; Westphal, Folker; Wagmann, Lea; Meyer, Markus R.
article2020Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass SpectrometryBambauer, Thomas P.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R.
article2020Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics DataHemmer, Selina; Manier, Sascha K.; Fischmann, Svenja; Westphal, Folker; Wagmann, Lea; Meyer, Markus R.
article2020Liquid Chromatography-High-Resolution Mass Spectrometry-Based In Vitro Toxicometabolomics of the Synthetic Cathinones 4-MPD and 4-MEAP in Pooled Human Liver MicrosomesManier, Sascha K.; Schwermer, Florian; Wagmann, Lea; Eckstein, Niels; Meyer, Markus R.
article2020Toxicokinetics and toxicodynamics of the fentanyl homologs cyclopropanoyl-1-benzyl-4´-fluoro-4-anilinopiperidine and furanoyl-1-benzyl-4-anilinopiperidineGampfer, Tanja M.; Wagmann, Lea; Park, Yu Mi; Cannaert, Annelies; Herrmann, Jennifer; Fischmann, Svenja; Westphal, Folker; Stove, Christophe P.; Meyer, Markus R.; Müller, Rolf
article2020Toxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adductsManier, Sascha K.; Wagmann, Lea; Flockerzi, Veit; Meyer, Markus R.
article2019In vitro metabolic fate of nine LSD-based new psychoactive substances and their analytical detectability in different urinary screening proceduresWagmann, Lea; Richter, Lilian; Kehl, Tobias; Wack, Franziska; Pettersson Bergstrand, Madeleine; Brandt, Simon D.; Stratford, Simon; Maurer, Hans H.; Meyer, Markus R.
article2019Toxicokinetic studies of the four new psychoactive substances 4-chloroethcathinone, N-ethylnorpentylone, N-ethylhexedrone, and 4-fluoro-alpha-pyrrolidinohexiophenoneWagmann, Lea; Manier, Sascha K.; Eckstein, Niels; Maurer, Hans H.; Meyer, Markus R.
article2019Method development for quantitative determination of seven statins including four active metabolites by means of high-resolution tandem mass spectrometry applicable for adherence testing and therapeutic drug monitoringWagmann, Lea; Hemmer, Selina; Caspar, Achim T.; Meyer, Markus
article2019Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screeningsWagmann, Lea; Hempel, Nora; Richter, Lilian H. J.; Brandt, Simon D.; Stratford, Alexander; Meyer, Markus R.
article2019Toxicokinetics and analytical toxicology of the abused opioid U-48800 - in vitro metabolism, metabolic stability, isozyme mapping, and plasma protein bindingGampfer, Tanja M.; Richter, Lilian H. J.; Schäper, Jan; Wagmann, Lea; Meyer, Markus R.
article2018Inhibition and stimulation of the human breast cancer resistance protein as in vitro predictor of drug–drug interactions of drugs of abuseWagmann, Lea; Maurer, Hans H.; Meyer, Markus R.
article2018Interactions of phenethylamine‐derived psychoactive substances of the 2C‐series with human monoamine oxidasesWagmann, Lea; Brandt, Simon D.; Stratford, Alexander; Maurer, Hans H.; Meyer, Markus R.
article2017An easy and fast adenosine 5'-diphosphate quantification procedure based on hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry for determination of the in vitro adenosine 5'-triphosphatase activity of the human breast cancer resistance protein ABCG2Wagmann, Lea; Maurer, Hans H.; Meyer, Markus R.
article2017In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risksWagmann, Lea; Brandt, Simon D.; Kavanagh, Pierce V.; Maurer, Hans H.; Meyer, Markus R.
article2016What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?Wagmann, Lea; Meyer, Markus R.; Maurer, Hans H.
Welcome
Name:Wagmann, Lea
Faculty: M - Medizinische Fakultät
Department: M - Experimentelle und Klinische Pharmakologie und Toxikologie
Professorship:M - Prof. Dr. Markus Meyer
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