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doi:10.22028/D291-33676
Titel: | Nanomaterials for the Diagnosis and Treatment of Inflammatory Arthritis |
VerfasserIn: | Hosseinikhah, Seyedeh Maryam Barani, Mahmood Rahdar, Abbas Madry, Henning Arshad, Rabia Mohammadzadeh, Vahideh Cucchiarini, Magali |
Sprache: | Englisch |
Titel: | International Journal of Molecular Sciences |
Bandnummer: | 22 |
Heft: | 6 |
Verlag/Plattform: | MDPI |
Erscheinungsjahr: | 2021 |
Freie Schlagwörter: | nanodiagnosis nanotreatments inflammatory arthritis |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Nanomaterials have received increasing attention due to their unique chemical and physical properties for the treatment of rheumatoid arthritis (RA), the most common complex multifactorial joint-associated autoimmune inflammatory disorder. RA is characterized by an inflammation of the synovium with increased production of proinflammatory cytokines (IL-1, IL-6, IL-8, and IL-10) and by the destruction of the articular cartilage and bone, and it is associated with the development of cardiovascular disorders such as heart attack and stroke. While a number of imaging tools allow for the monitoring and diagnosis of inflammatory arthritis, and despite ongoing work to enhance their sensitivity and precision, the proper assessment of RA remains difficult particularly in the early stages of the disease. Our goal here is to describe the benefits of applying various nanomaterials as next-generation RA imaging and detection tools using contrast agents and nanosensors and as improved drug delivery systems for the effective treatment of the disease. |
DOI der Erstveröffentlichung: | 10.3390/ijms22063092 |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-336760 hdl:20.500.11880/31001 http://dx.doi.org/10.22028/D291-33676 |
ISSN: | 1422-0067 |
Datum des Eintrags: | 30-Mär-2021 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Orthopädie |
Professur: | M - Prof. Dr. Henning Madry |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
Datei | Beschreibung | Größe | Format | |
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ijms-22-03092.pdf | 11,33 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons